The cannabis plant produces a wide variety of molecules. These include more than 100 cannabinoids. Clinical trials and animal studies have demonstrated the potential of THC and CBD. But as more cannabinoids begin to be studied, there is great excitement about other compounds such as cannabigerol (CBG). Let’s compare CBG vs. CBD. Scientists have discovered that it has numerous promising traits. This has piqued the interest of companies and researchers alike.
What is CBG?
The Israeli specialist in organic chemistry and “godfather” of cannabinoids, Raphael Mechoulam, was the first to isolate CBG. He tested it on rhesus monkeys, to which he administered this molecule. Along with THC, in 1964. Shortly after that, research published in the journal Psychopharmacology observed no behavioural changes.
CBG is classified as a secondary cannabinoid. Therefore, it was concluded that it is not psychoactive. However, some breeders have developed chemotypes with a 100% CBG profile by eliminating certain enzymes. These strains are to garner a lot of attention as CBG research progresses.
Researchers have labeled CBG as the “parent” or “stem cell” cannabinoid. It is the primary chemical precursor to many other cannabinoids. Certain enzymes convert CBG into corresponding molecules. People know this as cannabinoid biosynthesis.
All cannabinoids are the first cannabinoid acids in the raw plant. Elevated temperatures cause a reaction known as decarboxylation. That removes a carboxyl group from each molecule. This reaction transforms, for example, THCA in THC and CBDA in CBD. According to this theory, CBG is present as CBGA in the raw plant.
The CBGA synthase enzyme converts various organic compounds into CBGA. And additional enzymes break down the parent molecule into the main cannabinoids, depending on the reactions. THCA, CBDA, and CBCA synthases use CBGA as a substrate. To produce their respective cannabinoid acids. And other non-enzymatic processes produce more than 60 cannabinoids from CBGA.
What is CBD?
Cannabidiol is one of more than 100 cannabinoids present in the Cannabis plant. And along with Tetrahydrocannabinol or THC, they are the two most abundant in the cannabis plant. A recent WHO study considers CBD cannabidiol as a non-addictive compound. Unlike THC (Tetrahydrocannabinol), known for its euphoriant or psychoactive effects, CBD has no psychoactive effects. With almost no side effects.
Given its low level of toxicity and high therapeutic potential, CBD cannabidiol is gaining prominence. It is a natural alternative for many ailments. Every day we find new research studies that certify the power of CBD for the treatment of chronic pain. Also, oncological therapies, epilepsy, panic attacks, etc. As well as being an excellent antioxidant. It has anti-inflammatory, anxiolytic, anti-tumor, and anti-depressive properties.
Let’s remember that cannabinoids are part of the defence system of the cannabis plant. They protect it from predators and pests. That’s why the number of benefits CBD can bring should come as no surprise.
CBG Vs. CBD: Which One is Better?
CBD and CBG have several similarities and differences. But comparing these cannabinoids at this point in the research is relatively useless. CBD is much better studied. There could be other similarities and differences that we are not aware of. But let’s take a look at what we do know.
CBD and CBG have a low affinity for the CB1 receptor. CBG acts as a partial agonist of this receptor. At the same time, THC produces its psychotropic effects by stimulating this area of the central nervous system.
However, both CBD and CBG also function as CB1 receptor antagonists. They temporarily inhibit the uptake of the endocannabinoid anandamide. They stimulate it to a point where it does not cause psychotropic effects. The non-psychotropic nature of CBG and CBD makes them very attractive for clinical studies since many consider the “high” of THC to be an adverse side effect.
Is CBG Or CBD Better for Anxiety?
Although CBG is less well known, we are convinced that it can become just as famous as CBD. However, these compounds have some properties in common. CBG has its own unique and potent effects. Like CBD, CBG can be a powerful supplement. Against pain, inflammation, anxiety, and stress, as well as having antibacterial characteristics.
CBD (cannabidiol) has gained an excellent reputation in recent years. It has become a supplement to combat anxiety and stress. To name just a few of its uses. CBG (cannabigerol) is another cannabinoid produced by hemp or cannabis plants. It is primarily known as an ingredient in full-spectrum CBD products. However, CBG is entirely suitable for use on its own. So we could say that CBD and CBG are both useful for anxiety.
Is CBG A Better Pain Reliever Than CBD?
Chronic pain is an ailment that is identified by its duration. A pain that lasts less than three months is acute. On the other hand, chronic pain is characterized by lasting from 3 to 6 months. Or even longer. This is primarily a severe symptom of different conditions. It could be said that it is common in the most severe diseases in which pain is a primary symptom.
In this way, we can say that chronic pain symptoms are diseases or conditions that cause it. For example, pain in advanced-stage cancer disease. Pain in arthritis in severe stages. Neuralgia is caused by nerve damage. Severe back pain. In general, any ailment that is of significant impact is accompanied by wounds that do not heal. The classification of chronic pain will be in the same way.
In this case, the patient presents for months of intense pain. Which very little attenuates with conventional or low-dose analgesics. This is why many resort to more potent medications to help relieve. This ailment can cause a series of disorders at the neuronal level since the patient becomes irritable and is affected by poor sleep or no sleep at all.
Can I Take CBG And CBD Together?
In addition to having no psychoactive effects, CBD and CBG share many therapeutic properties. They can act synergistically when used together and offer a more beneficial effect. Compared to when they are used separately. This cooperation between various components of the Cannabis plant to obtain a more potent effect. It is called entourage or synergistic effect.
For example, both CBD and CBG have a neuroprotective effect. However, CBG achieves this by stimulating the production of proteins called BDNFs. In contrast, CBD acts by raising the levels of anandamide. This is a neuroprotectant that modulates CB1 receptors. Therefore, although they are different in several aspects, CBD and CBG could be a great combination if consumed together. The neuroprotective aspect of these two Cannabinoids together has been mainly studied. Pointing out that their effects are enhanced when combined.
While CBG, in its entirety, cannabigerol, is a cannabinoid that can provide you with many health benefits. CBD continues to maintain greater brand awareness. This makes sense since science and consumers have known about CBD for many years.
Cannabinoids are formed in or on the flowers of mature cannabis plants. Their function is to protect the plants against extreme climatic influences and vermin. CBG in its raw form is CBGA (cannabigerolic acid). And is the mother cell of cannabinoids such as THC, CBD, and CBC.
CBG is generally only present in small plants since CBGA is mainly converted into more abundant cannabinoids. Like CBD, CBG also interacts with your body’s endocannabinoid system. The two compounds offer different, overlapping health benefits. More and more research is being done on the medicinal effect of cannabis and now also on CBG. Numerous studies show that CBG itself has many benefits to offer. This applies to any type of use, topically or orally.
Both CBD and CBG interact with different pain receptors in the body. They ensure that pain signals to the brain are slow down. They also contribute to the relaxation of tense or spastic muscles. Pain can make daily activities suddenly less regular. This, in turn, creates stress, which creates a negative cycle. Taking CBD or CBG can, as described above, help you relax. Or that often has a beneficial effect on pain, as described above. Which often has a beneficial effect on pain as well.
With overlapping benefits, both types of cannabinoids provide health benefits. Still, some studies show that CBG is more effective than CBD for treating certain conditions. Of course, you can take advantage of both cannabinoids. To do this, use a combination of CBD and CBG oil. The amounts depend on your complaints. If you have a typical CBG complaint, you might consider using a little more CBG oil. With a ‘CBD complaint,’ of course, you do it the other way around. Sometimes, it may be a good idea to use only one of the two cannabinoids. A reliable seller should be able to advise you on this.